Diagnostic point-of-care tests in resource-limited settings

An Assessment of the Technological Issues and Options for Point-Of-Care Diagnostic Tests in Resource-Limited Settings

Feasibility of HIV point-of-care tests for resource-limited settings: challenges and solutions

Improved access to anti-retroviral therapy increases the need for affordable monitoring using assays such as CD4 and/or viral load in resource-limited settings. Barriers to accessing treatment, high rates of loss to initiation and poor retention in care are prompting the need to find alternatives to conventional centralized laboratory testing in certain countries. Strong advocacy has led to a r...

HIV Care & PMTCT in Resource-Limited Settings

edited. Objectives: We aimed to compare the incidence of meningococcal disease amongst HIV-infected and uninfected individuals and to evaluate whether HIV is a risk factor for mortality and bacteremia amongst patients with meningococcal disease. Design: Cohort surveillance study. Methods: We conducted laboratory-based surveillance for meningococcal disease in Gauteng Province, South Africa. HIV...

Maximizing the Delivery Performance of Point-of-Care CD4+ T-Cell Counting Tests in Resource-Limited Settings - A Policy Brief

Managing HIV/AIDS presents challenges to public health policymakers, frontline workers, and researchers worldwide. A key strategy in the disease management is early diagnosis and rapid treatment initiation. While the technological field of point‐of‐care HIV/AIDS diagnostics has advanced significantly in the past two decades, several critical issues remain that hinder the deployment of point‐of‐...

A Diagnostic Scoring Model for Leptospirosis in Resource Limited Settings

BACKGROUND Leptospirosis is a zoonotic infection with significant morbidity and mortality. The clinical presentation of leptospirosis is known to mimic the clinical profile of other prevalent tropical fevers. Laboratory confirmation of leptospirosis is based on the reference standard microscopic agglutination test (MAT), direct demonstration of the organism, and isolation by culture and DNA det...